Injections
Polynucleotides
Polynucleotide treatment
Polynucleotides are purified DNA fragments, usually derived from salmon or trout DNA, that undergo an advanced purification process ensuring high biological compatibility.
The treatment works by creating an optimal environment for tissue renewal, encouraging fibroblast activity and accelerating the body’s natural healing processes. As a result, collagen and elastin production increases, the extracellular matrix improves, and tissue quality rises over time.
Unlike fillers, polynucleotides are not intended to add volume but to improve skin quality from within. The treatment helps improve skin texture, elasticity, hydration, and natural radiance while encouraging natural renewal and tissue repair.
It is especially suitable for skin with early signs of aging, declining quality, fine wrinkles, and loss of elasticity, and is part of a Regenerative Aesthetics approach focused on repairing and renewing tissue rather than only external care.
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What is polynucleotide treatment?
Polynucleotide treatment is a gentle injection that helps the skin renew from within. Instead of adding volume or changing facial contours, it improves skin quality, texture, hydration, and elasticity.
Improvement builds gradually over weeks, so the result looks natural. It is especially suitable for anyone whose skin looks tired, thin, or damaged and who wants to strengthen it gently, without an “overdone” look.
Treatment benefits
- Improved skin quality
- Improved elasticity and flexibility
- Improved skin hydration
- Improved skin texture
- Reduction of fine wrinkles
- Encouragement of healing and renewal processes
- Repair of damaged skin
- Support for tissue repair processes
DNA-based skin renewal
The therapeutic approach relies on supporting the cellular environment and natural repair processes, with emphasis on tissue quality rather than immediate volume shaping.
Polynucleotides are therefore used in delicate areas such as around the eyes, and in conditions such as acne scars or pigmentation changes, according to skin quality and individual suitability.
Treatment areas
Polynucleotides are used to improve skin quality and repair tissue.
Common treatment areas
Eye area
- Improved skin quality
- Improved elasticity
- Softening of fine wrinkles
- Improvement of tired-looking skin
Face
- Improved skin quality
- Treatment of acne scars
- Improved skin texture
- Support for pigmentation treatment
Neck and décolletage
- Improved tissue quality
- Improved firmness and elasticity
Treatment of acne scars
Polynucleotides are an important tool in restoring skin affected by acne scars.
By encouraging fibroblast activity and new collagen production, the treatment helps improve tissue quality and reduce irregularities in skin texture.
The treatment may help with:
- Improved skin texture
- Softening of acne scars
- Improved tissue quality
- Improved skin flexibility
- Encouragement of new collagen formation
- Acceleration of renewal processes
Hyperpigmentation
Polynucleotides may help repair skin after sun damage, inflammation, or post-acne and improve skin quality and texture as part of a comprehensive treatment plan.
The treatment may contribute to:
- More even skin tone
- Improved skin quality
- Improved skin radiance
- Support for natural renewal processes
- Treatment duration
- About 30–45 minutes
- Discomfort level
- When results begin
- Initial improvement after about 2–4 weeks, with skin quality continuing to improve over the following months as tissue renewal progresses.
- Number of treatments
- Usually a series of 3 treatments, spaced 3–4 weeks apart, according to skin condition and treatment goals.
- Duration of effect
- About 6–12 months. Maintenance treatments are recommended according to skin condition and the physician’s advice.
Questions & answers
How does the treatment work?
They work by improving the cellular environment, encouraging natural healing processes, and boosting collagen and elastin production.
Treatment benefits
- Improved skin quality
- Improved elasticity and flexibility
- Improved skin hydration
- Improved skin texture
- Reduction of fine wrinkles
- Encouragement of healing and renewal processes
- Repair of damaged skin
- Support for tissue repair processes
The treatment is mainly aimed at improving skin quality rather than creating volume.
Who is the treatment suitable for?
Polynucleotides are suitable for men and women who want to improve tissue quality and encourage the skin's natural renewal processes, without adding volume or significantly changing facial features.
The treatment is especially suitable for areas where the skin is thin and delicate, or where there is a decline in skin quality, elasticity and vitality, including:
- Eye area – to improve skin quality, texture and elasticity, reduce the appearance of fine lines and give a fresher, more vibrant look.
- Face – to improve skin quality, texture, elasticity and vitality, and to encourage the skin's natural renewal processes.
- Neck and décolletage – to improve tissue quality, skin texture and early signs of aging.
- Acne scars – as part of a treatment plan designed to support tissue repair processes and gradually improve skin texture.
- Hyperpigmentation – as part of a treatment plan tailored to the type of pigmentation and the condition of the skin, aimed at improving tissue quality and supporting the skin's natural renewal processes.
In many cases, polynucleotides are part of a broader treatment plan that combines complementary treatments according to the medical diagnosis, the condition of the skin and the treatment goals. Combining treatments is intended to address the different mechanisms that affect skin and tissue quality, and the treatment plan is tailored individually to each patient.
How many treatments are needed?
In most cases a series of treatments is recommended, depending on the condition of the skin, the treatment goals and the medical assessment.
The number of treatments, the intervals between them and the need for maintenance treatments are tailored individually to each patient.
When are results visible?
Results are not immediate.
After treatment, a gradual process of tissue repair and natural collagen production begins, so the improvement appears gradually over the weeks following treatment and may continue to improve for several months.
The pace at which results appear varies between patients and depends on the condition of the skin, age, lifestyle and individual biological response.
Does the treatment add volume?
No.
Polynucleotides are not intended to create volume or reshape facial features. Their purpose is to improve tissue quality and encourage natural renewal processes, so the result is subtle and gradual.
What are the possible side effects?
After treatment, local side effects may appear, which in most cases are mild and temporary, including:
- Redness
- Mild swelling
- Sensitivity in the treated area
- Small bruises at the injection points
In most cases these effects resolve on their own within a few days.
As with any medical treatment, there are also rarer risks and side effects. Before treatment begins, a full medical assessment is carried out, during which the benefits, possible risks, alternatives and aftercare instructions are explained.
Combination with other treatments
Often the best results are achieved by combining several biostimulators and different regenerative technologies to encourage the body’s natural renewal mechanisms and achieve a natural, high-quality, long-lasting result.
In many cases they can also be combined with fillers, according to skin quality and treatment goals.
In summary
Polynucleotides are purified DNA fragments that encourage tissue repair and cellular renewal to improve skin quality rather than create volume.
The plan is tailored to skin quality and treatment goals at a consultation.