Hyperhidrosis

Primary hyperhidrosis is a disorder in which sweat glands work beyond what is needed for heat regulation and impair quality of life. Botulinum toxin temporarily blocks the nerve signal to the gland.

What primary hyperhidrosis is

Hyperhidrosis most often affects the underarms, palms, soles, or face. A secondary cause (for example thyroid disease or medication) should be ruled out before symptomatic treatment.

What the evidence shows

The approved Botox indication is severe axillary hyperhidrosis that did not respond adequately to topical treatment. Use in other areas is common clinically but off-label: controlled trials showed significant reduction in palmar sweating, with reports for face and scalp. Evidence for the feet is more limited.

Possible side effects include injection pain and, in the palms, temporary grip weakness. Dose and placement are set by area and functional risk.

Treatments that may help

These links go to treatments offered at the clinic that are clinically relevant to this condition. The final choice is made only after personal diagnosis.

Information on this page is general and is not a substitute for medical advice, diagnosis, or a treatment plan.